Tag: heal with food

Nurturing Harmony Within: The Interconnection of Gut Health and Stress Management

by Roxy Functional Wellness, posted in Health & Wellness, stress management

In the bustling symphony of life, stress has become an omnipresent tune, often overpowering our mental and physical well-being. However, amidst the chaos, there lies a silent conductor orchestrating the harmony between our body and mind – our gut health. From a functional medicine and holistic perspective, the interplay between gut health and stress management unveils a profound connection that goes beyond mere digestion. Let’s embark on a journey to explore why gut health matters, its impact on stress management, and delve into actionable tips rooted in holistic practices to foster optimal gut health.

Photo by Tanja Nikolic on Pexels.com

Why Gut Health Matters:

In the intricate web of our physiology, the gut is not merely a digestive organ but a central hub of vitality and resilience. It houses trillions of microbes collectively known as the gut microbiota, intricately linked with various aspects of our health, including immunity, metabolism, and even mood regulation. When the balance of this microbiota is disrupted, often termed dysbiosis, it can pave the way for a myriad of health issues, including heightened stress response and compromised mental well-being.

Impact of Gut Health on Stress Management:

The gut-brain axis, a bidirectional communication pathway between the gut and the brain, serves as a pivotal link in understanding the profound influence of gut health on stress management. Research suggests that an imbalance in gut microbiota can trigger inflammatory responses and alter neurotransmitter production (Highly suggest reading The Mind-Gut Connection by Emeran Mayer MD), contributing to mood disorders such as anxiety and depression. Moreover, the gut microbiota plays a crucial role in regulating the hypothalamic-pituitary-adrenal (HPA) axis, the body’s central stress response system.

Benefits of Good Gut Health:

Cultivating a thriving gut ecosystem yields a plethora of benefits extending far beyond digestion. Optimal gut health can bolster immune function, enhance nutrient absorption, and promote mental clarity and emotional resilience. Moreover, it serves as a cornerstone for overall vitality and longevity, fostering a harmonious balance within the body. I have seen this occur personally in my own journey to heal my gut. I have suffered from severe migraine headaches for years. Adding in a supportive gut regimen and removing diary has left me almost completely headache-free. As a bonus, I also sleep much better now!

Navigating the Gut Terrain: Common Disruptors of Gut Health

In the intricate tapestry of gut health, numerous disruptors weave their threads, casting shadows on the delicate balance within. Hormone disruptors, prevalent in environmental toxins and certain medications, can wreak havoc on the gut microbiota, triggering inflammation and compromising gut integrity. Poor sleep habits disrupt circadian rhythms, impairing gut motility and immune function, while a diet laden with processed foods and artificial additives fuels dysbiosis and intestinal permeability. Chronic stress, a ubiquitous companion in modern life, unleashes a cascade of hormonal imbalances and inflammatory responses, disrupting gut-brain communication and exacerbating digestive woes. Environmental toxins, from pesticides to heavy metals, assail the gut’s resilience, impeding detoxification pathways and fostering microbial imbalance. Amidst this labyrinth of disruptors, cultivating awareness and embracing holistic practices become paramount in safeguarding the sanctity of gut health and nurturing vitality from within.

“Quite literally, your gut is the epicenter of your mental and physical health. If you want better immunity, efficient digestion, improved clarity and balance, focus on rebuilding your gut health.” – Kris Carr

Tips for Improving Gut Health

So how can we improve our gut health and achieve our best mental health? There are multiple options that can be incorporated into one’s daily regimen. The key is that everyone’s gut regimen should be individualized to meet their body’s needs. Some starting options to improve gut include:

  1. Foundations of Health: Nourish your body with whole, unprocessed foods rich in fiber, prebiotics, and probiotics. Embrace a diverse array of plant-based foods, fermented foods like kimchi and sauerkraut, and incorporate healthy fats such as omega-3s found in fatty fish and flaxseeds. My husband and I love adding an organic Kombucha drink to our diet a few times per week as well as a shot of organic aloe vera juice nightly.
  2. Supplements and Herbs: Supplement your diet with gut-supportive nutrients like glutamine, zinc, and vitamin D, which play crucial roles in gut integrity and immune function. Additionally, consider incorporating herbs such as ginger, peppermint, marshmallow root, slippery elm, and licorice root, renowned for their soothing properties on the digestive system. Some wonderful combination products by clean organizations include:
    • Thorne – Saccharomyces Boulardii: Saccharomyces boulardii is a beneficial yeast that has been extensively studied for its ability to support gastrointestinal health. It helps maintain a healthy balance of gut flora, supports immune function in the gut, and promotes regularity. Thorne’s Saccharomyces Boulardii supplement provides a high-quality source of this probiotic yeast.
    • Allergy Research Group – Colostrum: Colostrum is the first milk produced by mammals after giving birth, and it’s rich in immune-boosting compounds, growth factors, and antibodies. Colostrum supplements are often used to support gut health by promoting the growth of beneficial bacteria, supporting the integrity of the intestinal lining, and modulating immune function. Allergy Research Group offers a high-quality Colostrum supplement sourced from grass-fed cows. This would not be one that would be appropriate for those that have a lactose allergy.
    • DesBio – GI Synergy and Intestinal Restore: These are two of my favorites! GI Synergy and Intestinal Restore are comprehensive gastrointestinal support formulas that combines a blend of herbs, enzymes, probiotics, and nutrients to promote optimal digestive function and gut health. They both contain a variety of ingredients such as slippery elm bark, marshmallow root, DGL (deglycyrrhizinated licorice), and zinc carnosine, which work synergistically to soothe and support the gastrointestinal tract. DesBio’s GI Synergy and Intestinal Restore supplement offers a convenient all-in-one solution for individuals looking to support their gut health.
  3. Homeopathic Remedies: Explore holistic remedies like lycopodium clavatum, pulsatilla, calc carb, and china. Some great homeopathic remedies and brands include:
    • DesBio – Lycopodium Clavatum: Derived from the spores of the clubmoss plant, Lycopodium clavatum is a homeopathic remedy often used to address digestive issues such as bloating, gas, and indigestion. It’s believed to help regulate digestion and alleviate symptoms associated with imbalances in the gut microbiota.
    • Boiron – Nux Vomica: Nux vomica, derived from the seeds of the strychnine tree, is a homeopathic remedy commonly used to address digestive disturbances such as nausea, heartburn, and constipation. It’s particularly beneficial for individuals with overindulgence in rich or spicy foods, alcohol, or caffeine, helping to restore balance to the digestive system.
  4. Mindful Eating: Mindful eating is not only good for gut health and stress management, but can also help in weight control. Some examples include:
    • Savoring Each Bite: Take the time to truly appreciate the flavors, textures, and aromas of your food. Engage all your senses as you eat, noticing the colors, smells, and sounds of your meal. Chew each bite slowly and thoroughly, paying attention to the sensations of the food in your mouth. By savoring each bite, you can cultivate a deeper appreciation for your meals and become more attuned to your body’s hunger and fullness cues.
    • Eating Without Distractions: Create a peaceful eating environment free from distractions such as television, phones, or computers. Sit down at a table and focus solely on the act of eating without multitasking. Take the time to tune into your body’s hunger and satiety signals, eating slowly and mindfully. By eating without distractions, you can fully immerse yourself in the experience of eating and foster a deeper connection with your food and body.
  5. Stress Management: Prioritize stress management techniques such as regular exercise, adequate sleep, and engaging in activities that bring joy and relaxation. Practice stress-reducing rituals like journaling, spending time in nature, or connecting with loved ones to nurture emotional well-being. Incorporate mindfulness practices such as meditation, yoga, and deep breathing exercises to alleviate stress and promote gut-brain harmony.

These supplement remedies, when used as part of a holistic approach to gut health, can provide support for digestive function, promote a balanced gut microbiota, and help maintain gastrointestinal comfort. As always, it’s important to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications.

Bringing It All Together!

Nurturing gut health is not merely about soothing digestive woes but fostering a profound synergy between body, mind, and spirit. By honoring the intricate dance of the gut-brain axis and embracing holistic principles, we pave the way for resilience, vitality, and inner harmony amidst life’s ebbs and flows. Let us embark on this journey with reverence for the innate wisdom that resides within, nurturing the sacred bond between gut health and stress management.

Written By: Roxanne Oliver, DNP, APRN, FNP-BC

Published: 04/13/2024

*The information contained in this post is for information only. It does not replace routine follow-up and/or care with a certified and licensed medical provider.

References

  1. Guarner, F., & Malagelada, J. R. (2003). Gut flora in health and disease. The Lancet, 361(9356), 512-519. doi:10.1016/s0140-6736(03)12489-0
  2. Rea, K., Dinan, T. G., & Cryan, J. F. (2016). The microbiome: A key regulator of stress and neuroinflammation. Neurobiology of Stress, 4, 23-33. doi:10.1016/j.ynstr.2016.03.001
  3. De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., … & Lionetti, P. (2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences, 107(33), 14691-14696. doi:10.1073/pnas.1005963107
  4. Konturek, P. C., Brzozowski, T., & Konturek, S. J. (2011). Stress and the gut: Pathophysiology, clinical consequences, diagnostic approach and treatment options. Journal of Physiology and Pharmacology, 62(6), 591-599.
  5. Gibson, P. R., & Shepherd, S. J. (2010). Evidence-based dietary management of functional gastrointestinal symptoms: The FODMAP approach. Journal of Gastroenterology and Hepatology, 25(2), 252-258. doi:10.1111/j.1440-1746.2009.06149.x
  6. Katterman, S. N., & Kleinman, B. M. (2014). Hood, mindfulness meditation, and eating: A review and guide for the practice. Journal of the Academy of Nutrition and Dietetics, 114(3), 392-402. doi:10.1016/j.jand.2013.12.026

Harnessing the Power of Green Tea: A Stress-Relief Elixir and Matcha Coconut Yogurt Bowl Recipe

by Roxy Functional Wellness, posted in Health & Wellness, stress management

Stress seems to be an inevitable part of our daily lives (I know it is in mine!). From hectic work schedules to family responsibilities, it’s easy to feel overwhelmed sometimes. However, amidst the chaos, there lies a natural remedy that has been cherished for centuries: green tea. Not only does green tea offer a plethora of health benefits, but it also has the potential to significantly improve stress management. Let’s delve into the wonders of green tea and explore one of my favorite breakfast recipes for a dairy-free matcha coconut yogurt bowl that incorporates the stress-relieving properties of green tea, chia seeds, and pumpkin seeds.

The Stress-Relieving Benefits of Green Tea:

  1. L-Theanine: Green tea contains an amino acid called L-theanine, which is known for its calming effects on the mind. L-theanine promotes relaxation without causing drowsiness, making it an excellent choice for stress relief.
  2. Antioxidants: Loaded with powerful antioxidants called catechins, green tea helps combat oxidative stress in the body. These antioxidants protect cells from damage and may reduce the risk of chronic diseases as it prevents the build up of inflammation in the body.
  3. Cortisol Regulation: Cortisol, often referred to as the stress hormone, can wreak havoc on our bodies when levels are elevated for prolonged periods. Studies suggest that green tea may help regulate cortisol levels, thereby promoting a more balanced stress response (Yes please!).
  4. Improved Brain Function: The combination of caffeine and L-theanine in green tea can enhance cognitive function and improve mood. This synergistic effect helps boost alertness and concentration while keeping stress at bay.

The Nutritional Powerhouses: Pumpkin Seeds and Chia Seeds:

Pumpkin Seeds:

  • Rich in magnesium, pumpkin seeds play a vital role in relaxation and stress reduction. Magnesium helps calm the nervous system and can promote better sleep quality. This then prevents the over-secretion of cortisol.
  • High in antioxidants like vitamin E and zinc, pumpkin seeds protect cells from damage caused by oxidative stress and support overall immune function.
  • The amino acid tryptophan found in pumpkin seeds aids in the production of serotonin, a neurotransmitter that regulates mood and promotes feelings of well-being.

Chia Seeds:

  • Packed with omega-3 fatty acids, chia seeds support brain health and help reduce inflammation in the body. A healthy brain is better equipped to cope with stress.
  • High in fiber, chia seeds promote digestive health and keep blood sugar levels stable, preventing energy crashes that can exacerbate stress.
  • Chia seeds are a good source of essential minerals like calcium, magnesium, and phosphorus, which play key roles in muscle relaxation and stress management.
  • Chia seeds are also one of the highest protein seeds that you can eat, which is a great bonus if you are trying to get your protein in.

Recipe: Dairy-Free Matcha Coconut Yogurt Bowl with Chia and Pumpkin Seeds

Ingredients:

  • 1 cup dairy-free coconut yogurt (you can always use Greek yogurt, but I am dairy-free)
  • 1 teaspoon matcha powder (preferably organic to prevent chemical/additive exposure)
  • 1 tablespoon maple syrup or honey (optional, for sweetness)
  • 1 tablespoon chia seeds
  • 1 tablespoon pumpkin seeds
  • Fresh berries (such as strawberries, blueberries, or raspberries), for topping
  • 1/8-1/4 cup of granola (I like Purely Elizabeth Vanilla Almond Butter)
  • Unsweetened coconut flakes or cacao nibs, for garnish.

Instructions:

  1. In a mixing bowl, combine the dairy-free coconut yogurt, matcha powder, and maple syrup or honey (if using). Stir until the matcha powder is fully incorporated and the yogurt is smooth.
  2. Sprinkle the chia seeds and pumpkin seeds over the yogurt mixture, and gently fold them in until evenly distributed.
  3. Transfer the matcha coconut yogurt mixture to serving bowls.
  4. Top each bowl with fresh berries of your choice, granola, and a sprinkle of unsweetened coconut flakes for added flavor and texture.
  5. Serve immediately and enjoy as a nutritious and stress-relieving breakfast or snack.

By incorporating green tea, pumpkin seeds, and chia seeds into your diet, you can harness the power of nature to combat stress and promote overall well-being. Whether enjoyed in a soothing cup of tea or as part of a delicious yogurt bowl, these wholesome ingredients offer a holistic approach to stress management that nourishes both body and mind. So, take a moment to sip on some green tea and savor the tranquility it brings to your day.

Written By: Roxanne Oliver, DNP, APRN, FNP-BC

Published: 04/13/2024

*The information contained in this post is for information only. It does not replace routine follow-up and/or care with a certified and licensed medical provider.

References

  1. Boyle, Neil B., et al. “The effects of magnesium supplementation on subjective anxiety and stress—a systematic review.” Nutrients 9.5 (2017): 429.
  2. Cabrera, Carmen, Reyes Artacho, and Rafael Giménez. “Beneficial effects of green tea—a review.” Journal of the American College of Nutrition 25.2 (2006): 79-99.
  3. Coelho, Christiane Candice, et al. “Omega-3-rich chia seed (Salvia hispanica L.) oil formulations ameliorate lipid profile of dyslipidemic subjects and associated oxidative stress: a randomized, double-blind, placebo-controlled study.” Nutrients 11.2 (2019): 341.
  4. Kimura, Kenta, et al. “L-Theanine reduces psychological and physiological stress responses.” Biological psychology 74.1 (2007): 39-45.
  5. Li, Kai, et al. “Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial.” Evidence-Based Complementary and Alternative Medicine 2014 (2014).
  6. Nieman, David C., et al. “Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation.” Journal of Alternative and Complementary Medicine 24.3 (2018): 293-299.
  7. Unno, Keiko, et al. “Anti-stress effect of green tea with lowered caffeine on humans: A pilot study.” Biological psychology 74.1 (2007): 39-45.
  8. Wang, H., N. F. Lucas, and P. N. Weil. “Pumpkin seed extracts and proteins: embryotoxicity and oxytocin-like effects.” Journal of ethnopharmacology 6.1 (1982): 201-208.

Harnessing the Power of Adaptogens for Stress Management and Beyond

by Roxy Functional Wellness, posted in Health & Wellness, stress management

In the fast-paced world we live in today, stress has become an almost inevitable part of our daily lives. Whether it’s the pressure at work, personal relationships, or the constant barrage of information, stress can take a toll on our physical and mental well-being. However, amidst the chaos, there lies a natural solution that has been utilized for centuries in various traditional medicine practices – adaptogens.

What Are Adaptogens?

Adaptogens are a unique class of herbs and mushrooms that help the body adapt to stressors, whether they are physical, chemical, or biological. These natural substances work by modulating the body’s stress response system, helping to restore balance and promote overall health and vitality. Unlike stimulants, adaptogens don’t push the body into overdrive (unlike coffee); instead, they work in a subtle and gentle manner to support the body’s natural resilience.

Common Examples of Adaptogens:

  1. Ashwagandha: Originating from traditional Ayurvedic medicine, ashwagandha is known for its ability to promote relaxation and reduce stress. It helps to balance cortisol levels, the hormone associated with stress, and supports overall adrenal health.
  2. Rhodiola Rosea: Native to the arctic regions of Europe and Asia, rhodiola is prized for its adaptogenic properties. It enhances mental performance, improves mood, and boosts endurance, making it a valuable ally in combating stress and fatigue.
  3. Holy Basil (Tulsi): Revered as a sacred plant in Ayurveda, holy basil is renowned for its ability to promote mental clarity and emotional well-being. It helps to reduce anxiety, uplift mood, and enhance resilience to stress. It can even help balance blood sugars!
  4. Reishi Mushroom: A staple in traditional Chinese medicine, reishi mushroom is often referred to as the “mushroom of immortality.” It supports the body’s natural defense mechanisms, strengthens the immune system, and promotes relaxation.
Where do you start?

Sometimes the hardest step in integrating adaptogens is knowing what brand to choose. It is always very important to research companies and the quality of ingredients that they use. It is counterintuitive to add adaptogens to your daily routine if they do not contain pure ingredients and/or contain additives, preservatives, heavy metals, etc… Some brands worth using include:

  1. Integrative Therapeutics Cortisol Manager: This popular supplement combines ashwagandha, L-theanine, magnolia bark, and phosphatidylserine to support healthy cortisol levels and promote relaxation. It’s a well-researched formula trusted by many for stress management. This is a personal favorite of mine that I use daily in the evenings before bed. Integrative Therapeutics is a tried and true brand with quality supplements.
  2. Gaia Herbs Adrenal Health Daily Support: Formulated with a blend of adaptogenic herbs including rhodiola, holy basil, and ashwagandha, this supplement helps to nourish and support the adrenal glands, promoting resilience to stress and fatigue.
  3. Allergy Research Group Zen Adapt: Crafted by Allergy Research Group, Zen Adapt is a premium adaptogenic supplement designed to promote relaxation and stress resilience. This unique formula combines a blend of adaptogenic herbs, including rhodiola, ashwagandha, as well as GABA and L-theanine, to support the body’s natural stress response. With a focus on purity and potency, Allergy Research Group ensures that Zen Adapt delivers high-quality ingredients backed by rigorous testing and research. Trusted by healthcare practitioners and wellness enthusiasts alike, Zen Adapt offers a gentle yet effective solution for managing stress and promoting overall well-being.
  4. Four Sigmatic Reishi Mushroom Elixir: Four Sigmatic specializes in mushroom-based supplements, and their Reishi Mushroom Elixir is a popular choice for stress management and relaxation. Made with organic reishi mushroom extract, this elixir can be easily added to hot water or your favorite beverage for a calming and immune-supporting boost. They also make fantastic coffee if you haven’t tried it!

As always, no matter what supplement is chosen, always follow package instructions. I also like to track how I feel for a couple days to a week whenever trying something new. This can help you discern if what you are taking is truly helping. Additionally, it is always good to consult with a licensed and certified medical practitioner if you have medical conditions and/or if you are taking other medications.

Adding Adaptogens into your diet

Integrating adaptogens does not always mean you have to add a supplement. Integrating adaptogens into your diet can be a delicious and convenient way to harness their stress-relieving and health-promoting benefits. Here are some ways to incorporate adaptogens into your daily meals and snacks:

  1. Herbal Teas: Brew a soothing cup of herbal tea infused with adaptogenic herbs like ashwagandha, holy basil, or licorice root. You can either use loose herbs or opt for pre-packaged herbal tea blends designed to promote relaxation and stress relief. My go to is Buddha Teas; specifically the Calm Buddha Blend.
  2. Smoothies: Add adaptogenic powders or tinctures to your morning smoothie for an extra boost of stress-busting goodness. Ingredients like ashwagandha powder, maca root powder, or rhodiola extract can easily be blended with fruits, leafy greens, and your choice of liquid for a nutritious and energizing beverage.
  3. Golden Milk: Golden milk, also known as turmeric latte, is a warming and comforting drink made with turmeric, spices, and milk (or a dairy-free alternative). Enhance its stress-relieving properties by adding adaptogens like ashwagandha powder or reishi mushroom extract for a soothing bedtime treat.
  4. Energy Balls: Whip up a batch of homemade energy balls or bars using adaptogenic ingredients like dates, nuts, seeds, and adaptogen powders such as maca or ashwagandha. These convenient snacks provide a quick and nourishing way to combat stress and boost energy levels throughout the day. This is my favorite option as they make for quick on-the-go snack!
  5. Soups and Stews: Incorporate adaptogenic herbs and mushrooms into your favorite soups and stews for a comforting and immune-supporting meal. Reishi mushrooms, astragalus root, and holy basil can add depth of flavor and health benefits to hearty dishes like chicken soup or vegetable stew.
  6. Salad Dressings: Create homemade salad dressings infused with adaptogenic herbs like rosemary, thyme, or sage. These aromatic herbs not only enhance the flavor of your salads but also provide antioxidant and anti-inflammatory benefits to support overall health and well-being. I find a lot of recipes on Pinterest that are easy to make and spruce up a salad in no time!
  7. Infused Oils and Vinegars: Make your own infused oils and vinegars using adaptogenic herbs and spices like garlic, ginger, or turmeric. Use these flavorful infusions to dress salads, marinate meats, or drizzle over roasted vegetables for a tasty and healthful addition to your meals.
Photo by Charlotte May on Pexels.com
Health Benefits Beyond Stress Management:

While adaptogens are widely known for their ability to support stress management, their benefits extend far beyond just that and are too good not to mention here. They include:

  1. Improved Energy and Stamina: Adaptogens help to optimize energy levels by supporting the body’s natural energy production pathways, making them valuable allies for combating fatigue and promoting vitality.
  2. Enhanced Mental Clarity and Focus: By reducing stress and supporting cognitive function, adaptogens can improve mental clarity, concentration, and overall cognitive performance.
  3. Balanced Mood and Emotional Well-being: Adaptogens have mood-regulating properties that help to reduce anxiety, uplift mood, and promote emotional balance, enhancing overall well-being.
  4. Immune System Support: Many adaptogens possess immune-modulating properties that help to strengthen the body’s natural defense mechanisms, making them valuable for maintaining immune health, especially during times of increased stress.

“Integrating adaptogens does not always mean you have to add a supplement. Integrating adaptogens into your diet can be a delicious and convenient way to harness their stress-relieving and health-promoting benefits.”

By incorporating adaptogens into your diet in creative and delicious ways, you can support your body’s natural resilience to stress and promote overall well-being from the inside out. Experiment with different adaptogenic herbs and recipes to discover what works best for you and enjoy the soothing benefits of these powerful botanicals. Whether it’s ashwagandha, rhodiola, holy basil, or reishi mushroom, incorporating adaptogens into our daily routine can be a transformative step towards a healthier and more resilient life.

Written By: Roxanne Oliver, DNP, APRN, FNP-BC

Published: 04/09/2024

*The information contained in this post is for information only. It does not replace routine follow-up and/or care with a certified and licensed medical provider.

References

  1. Kennedy, D. O., & Wightman, E. L. (2011). Herbal extracts and phytochemicals: Plant secondary metabolites and the enhancement of human brain function. Advances in Nutrition, 2(1), 32–50. https://doi.org/10.3945/an.110.000117
  2. Lopresti, A. L., Smith, S. J., Malvi, H., & Kodgule, R. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine, 98(37), e17186. https://doi.org/10.1097/md.0000000000017186
  3. Mishra, L. C., Singh, B. B., & Dagenais, S. (2000). Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): A review. Alternative Medicine Review, 5(4), 334–346.
  4. Panossian, A., & Wikman, G. (2009). Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Current Clinical Pharmacology, 4(3), 198–219. https://doi.org/10.2174/157488409789375311
  5. Panossian, A., & Wikman, G. (2010). Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity. Pharmaceuticals, 3(1), 188–224. https://doi.org/10.3390/ph3010188
  6. Panossian, A., & Wilkman, G. (2011). Pharmacology of Rhodiola rosea. Current Pharmaceutical Design, 17(35), 42-57. https://doi.org/10.2174/138161211795649485
  7. Panossian, A., & Wagner, H. (2005). Stimulating effect of adaptogens: An overview with particular reference to their efficacy following single dose administration. Phytotherapy Research, 19(10), 819–838. https://doi.org/10.1002/ptr.175
  8. Puri, D., & Sharma, R. (2012). Relevance of standardization and scientific validation of botanicals in herbal medicine. Journal of Chemical and Pharmaceutical Research, 4(1), 476–483.
  9. Sarris, J., McIntyre, E., & Camfield, D. A. (2013). Plant-based medicines for anxiety disorders, part 1: A review of preclinical studies. CNS Drugs, 27(3), 207–219. https://doi.org/10.1007/s40263-013-0041-0
  10. Singh, N., Bhalla, M., de Jager, P., & Gilca, M. (2011). An overview on ashwagandha: A Rasayana (rejuvenator) of Ayurveda. African Journal of Traditional, Complementary and Alternative Medicines, 8(5 Suppl), 208–213. https://doi.org/10.4314/ajtcam.v8i5s.9